Saltu al enhavo

Transferrin

Paĝenhavo ne ekzistas en aliaj lingvoj.
Krei artikolon

This is an automatic view based on data from Vikidatumoj.
There is not a complete article yet, but you can help creating one.

This template is part of the ArticlePlaceholder extension. If you want to adjust it, please consider making your changes upstream.

mammalian protein found in Homo sapiens

Eksteraj rimedoj

identigilo de Gran Enciclopèdia Catalana
0147397
0142397
identigilo de Freebase
/m/02dcmf[1]
numero en Microsoft Academic
22814914
identigilo de proteino laŭ RefSeq
NP_001054[2]
NP_001341633[2]
NP_001341632[2]
WordNet 3.1 Synset ID
15102484-n[3]
identigilo de proteino laŭ Ensembl
ENSP00000385834[4]
ENSP00000401505[5]
ENSP00000417468[6]
ENSP00000418396[7]
ENSP00000418716[8]
ENSP00000419338[9]
ENSP00000419714[10]
DeCS ID
22302
OpenAlex ID
C22814914[11]
NKCR-identigilo (Ĉeĥio)
ph323407

nomita kiel: transferin

difinita signifo en OmegaWiki
1495805
Gran Enciclopèdia Catalana ID
transferrina
UniProt protein ID
P02787[12]
PDB structure ID
4X1D[13]
1A8E[13]
1A8F[13]
1B3E[13]
1BP5[13]
1BTJ[13]
1D3K[13]
1D4N[13]
1DTG[13]
1FQE[13]
1FQF[13]
1JQF[13]
1N7W[13]
1N7X[13]
1N84[13]
1OQG[13]
1OQH[13]
1RYO[13]
1SUV[13]
2HAU[13]
2HAV[13]
2O7U[13]
2O84[13]
3FGS[13]
3QYT[13]
3S9L[13]
3S9M[13]
3S9N[13]
3SKP[13]
3V83[13]
3V89[13]
3V8X[13]
3VE1[13]
4H0W[13]
4X1B[13]
5DYH[13]

estas

proteino[12]

parto de

Serotransferrin, mammalian[14]
Transferrin-like domain, protein family[15]
Transferrin family, iron binding site, protein family[15]

en taksono

Homo sapiens[12]

kodata de

TF[12]

molekula funkcio

ferric iron binding[16]

determina metodo: IEA

metal ion binding[17]

determina metodo: IEA

proteina ligado[18][19][20][21][22][23][24][25][26][27]

determina metodo: IPI

ferric iron transmembrane transporter activity[16]

determina metodo: IEA

ferrous iron binding[28]

determina metodo: IDA

transferrin receptor binding[29][30][31]

determina metodo: spurebla aŭtora aserto, IPI

iron chaperone activity[28]

determina metodo: IDA

ĉelparto

recikliga endosomo[32]

determina metodo: IDA

veziketo[33]

determina metodo: IDA

HFE-transferrin receptor complex[34]

determina metodo: IDA

malfrua endosomo[32]

determina metodo: IDA

blood microparticle[35]

determina metodo: IDA

basal part of cell[32]

determina metodo: IDA

enĉela veziketo[36][37]

determina metodo: IDA

eksterĉela regiono[38][39][17][16][40]

determina metodo: NAS, IDA, IEA, spurebla aŭtora aserto

cell surface[41]

determina metodo: IDA

basal plasma membrane[32]

determina metodo: IDA

extrinsic component of external side of plasma membrane[42]

determina metodo: IGI

frua endosomo[32]

determina metodo: IDA

apical plasma membrane[43]

determina metodo: IDA

perinuclear region of cytoplasm[32][44]

determina metodo: IDA

clathrin-coated pit[45]

determina metodo: IDA

secretory granule lumen[38]

determina metodo: spurebla aŭtora aserto

endosoma membrano[38]

determina metodo: spurebla aŭtora aserto

extracellular exosome[46][47][48]

determina metodo: IDA

eksterĉela spaco[49][50][51][52]

determina metodo: IDA, IEA

clathrin-coated vesicle membrane[38]

determina metodo: spurebla aŭtora aserto

citoplasma veziketo[45]

determina metodo: IDA

endoplasmic reticulum lumen[38]

determina metodo: spurebla aŭtora aserto

eksterĉela spaco[16][53][54][55]

determina metodo: HDA, IEA

extracellular exosome[56][57]

determina metodo: HDA

blood microparticle[58]

determina metodo: HDA

biologia procezo

positive regulation of receptor-mediated endocytosis[42][59]

determina metodo: IDA, IGI

cellular response to iron ion[42]

determina metodo: IGI

regado de proteina stabileco[60]

determina metodo: spurebla aŭtora aserto

transferrin transport[38]

determina metodo: spurebla aŭtora aserto

ferjona homeostato[17][61]

determina metodo: IC, IEA

platelet degranulation[38]

determina metodo: spurebla aŭtora aserto

jona transporto[17]

determina metodo: IEA

retina homeostasis[62]

determina metodo: IEP

iron ion transport[16]

determina metodo: IEA

ĉela ferjona homeostato[38][16]

determina metodo: spurebla aŭtora aserto, IEA

membrane organization[38]

determina metodo: spurebla aŭtora aserto

posttraduka modifo de proteino[38]

determina metodo: spurebla aŭtora aserto

biologia transportado[63]

determina metodo: IEA

retina homeostasis[64]

determina metodo: HEP

iron ion transmembrane transport[65]

determina metodo: IEA

regulation of iron ion transport[42]

determina metodo: IGI

Gene Atlas image

plene kongruas kun

http://purl.uniprot.org/uniprot/P02787[66]

havas parton

Transferrin family, iron binding site[14]
Transferrin-like domain[14]

Referenco

  1. ↑ Freebase Data Dumps, 28 okt. 2013
  2. ↑ 2,0 2,1 2,2 NCBI Gene, 30 maj. 2020, 7018
  3. ↑ GF WordNet
  4. ↑ Ensembl Release 99, ENSP00000385834
  5. ↑ Ensembl Release 99, ENSP00000401505
  6. ↑ Ensembl Release 99, ENSP00000417468
  7. ↑ Ensembl Release 99, ENSP00000418396
  8. ↑ Ensembl Release 99, ENSP00000418716
  9. ↑ Ensembl Release 99, ENSP00000419338
  10. ↑ Ensembl Release 99, ENSP00000419714
  11. ↑ OpenAlex, 26 jan. 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  12. ↑ 12,0 12,1 12,2 12,3 UniProt, 13 nov. 2019, P02787
  13. ↑ 13,00 13,01 13,02 13,03 13,04 13,05 13,06 13,07 13,08 13,09 13,10 13,11 13,12 13,13 13,14 13,15 13,16 13,17 13,18 13,19 13,20 13,21 13,22 13,23 13,24 13,25 13,26 13,27 13,28 13,29 13,30 13,31 13,32 13,33 13,34 13,35 P02787, 9 aŭg. 2016, UniProt, angla lingvo
  14. ↑ 14,0 14,1 14,2 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P02787
  15. ↑ 15,0 15,1 inferred from protein domain or family
  16. ↑ 16,0 16,1 16,2 16,3 16,4 16,5 IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, InterPro, GOA
  17. ↑ 17,0 17,1 17,2 17,3 IEA, 8 apr. 2019, P02787, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  18. ↑ IPI, 8 apr. 2019, P02787, Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  19. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, Structural basis for iron piracy by pathogenic Neisseria, GOA
  20. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, Mechanism for multiple ligand recognition by the human transferrin receptor, GOA
  21. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax., GOA
  22. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH, GOA
  23. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, The molecular mechanism for receptor-stimulated iron release from the plasma iron transport protein transferrin, GOA
  24. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, The structural basis of transferrin sequestration by transferrin-binding protein B, GOA
  25. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, Noncanonical interactions between serum transferrin and transferrin receptor evaluated with electrospray ionization mass spectrometry, GOA
  26. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro, GOA
  27. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, IntAct protein interaction database, Release of the soluble transferrin receptor is directly regulated by binding of its ligand ferritransferrin, GOA
  28. ↑ 28,0 28,1 IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
  29. ↑ spurebla aŭtora aserto, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding, GOA
  30. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor, GOA
  31. ↑ IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
  32. ↑ 32,0 32,1 32,2 32,3 32,4 32,5 IDA, 8 apr. 2019, P02787, Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  33. ↑ IDA, 8 apr. 2019, P02787, A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  34. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor, GOA
  35. ↑ IDA, 17 okt. 2017, P02787, Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  36. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, Mouse Genome Informatics, Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment, GOA
  37. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, Mouse Genome Informatics, Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes, GOA
  38. ↑ 38,00 38,01 38,02 38,03 38,04 38,05 38,06 38,07 38,08 38,09 spurebla aŭtora aserto, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, Reactome, GOA
  39. ↑ NAS, 8 apr. 2019, P02787, The human plasma proteome: a nonredundant list developed by combination of four separate sources, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  40. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum, GOA
  41. ↑ IDA, 8 apr. 2019, P02787, Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  42. ↑ 42,0 42,1 42,2 42,3 IGI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
  43. ↑ IDA, 8 apr. 2019, P02787, Truncated brush border myosin I affects membrane traffic in polarized epithelial cells, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  44. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, Community Assessment of Community Annotation with Ontologies, Ebola virus uses clathrin-mediated endocytosis as an entry pathway, GOA
  45. ↑ 45,0 45,1 IDA, 8 apr. 2019, P02787, Myo6 facilitates the translocation of endocytic vesicles from cell peripheries, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  46. ↑ IDA, 17 okt. 2017, P02787, Large-scale proteomics and phosphoproteomics of urinary exosomes, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  47. ↑ IDA, 17 okt. 2017, P02787, In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  48. ↑ IDA, 17 okt. 2017, P02787, Proteomic analysis of podocyte exosome-enriched fraction from normal human urine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  49. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, 17 okt. 2017, InterPro, GOA
  50. ↑ IDA, 17 okt. 2017, P02787, Human colostrum: identification of minor proteins in the aqueous phase by proteomics, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  51. ↑ IDA, 17 okt. 2017, P02787, Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  52. ↑ IDA, 17 okt. 2017, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  53. ↑ HDA, 8 apr. 2019, P02787, Human colostrum: identification of minor proteins in the aqueous phase by proteomics, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  54. ↑ HDA, 8 apr. 2019, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  55. ↑ HDA, 8 apr. 2019, P02787, Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  56. ↑ HDA, 8 apr. 2019, P02787, Large-scale proteomics and phosphoproteomics of urinary exosomes, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  57. ↑ HDA, 8 apr. 2019, P02787, In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  58. ↑ HDA, 8 apr. 2019, P02787, Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  59. ↑ IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells, GOA
  60. ↑ spurebla aŭtora aserto, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression, GOA
  61. ↑ IC, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, British Heart Foundation, HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron, GOA
  62. ↑ IEP, 17 okt. 2017, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  63. ↑ IEA, 17 okt. 2017, P02787, GOA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P02787&geneProductId=UniProtKB:P02787, UniProt
  64. ↑ HEP, 8 apr. 2019, P02787, Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy, GOA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, UniProt
  65. ↑ IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02787, 8 apr. 2019, Geno-Ontologia Konsorcio, GOA
  66. ↑ Identifiers.org
Elŝutita el "https://eo.wikipedia.org/wiki/Specialaĵo:AboutTopic/Q410473"