erythromycin
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kemia kombinaĵo
estas
speco de kemiaĵo
subaro de
macrolides
erythromycin
kemia strukturo
uzita kriterio: structure representation with unlabelled terminal carbon atoms
uzita kriterio: structure representation with labelled terminal carbon atoms
maso
733,461 daltono[26]
stereoizomero de
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5R,6R)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione[44]
kemia formulo
C₃₇H₆₇NO₁₃[26]
ĉefforma SMILES
CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O[26]
izomera SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O[26]
aktiva ingredienco en
Erythrocin Stearate[45]
Erythrocin[46]
Ery-Tab[47]
Erygel[48]
EryPed[49]
PCE[50]
Ery[51]
Emcin Clear[52]
Emgel[53]
E.E.S.[54]
Internacia Nekomerca Nomo de medikamento laŭ Internacia Organizaĵo pri Sano
erythromycin[25]
en taksono
Aeromicrobium erythreum[55]
Streptomyces hygroscopicus[56]
Streptomyces albidoflavus[65]
Streptomyces coelicolor[65]
Bacillus subtilis[66]
Pseudoalteromonas[67]
significant drug interaction
amiodarone[70]
anagrelide[70]
astemizole[70]
azithromycin[70]
bepridil[70]
cisapride[70]
(RS)-citalopram[70]
clarithromycin[70]
disopyramide[70]
dofetilide[70]
dronedarone[70]
droperidol[70]
escitalopram[70]
flecainide[70]
halofantrine[70]
haloperidol[70]
ibutilide[70]
mesoridazine[70]
moxifloxacin[70]
pimozide[70]
probucol[70]
procainamide[70]
sevoflurane[70]
sotalol[70]
sparfloxacin[70]
(RS)-sulpiride[70]
terfenadine[70]
thioridazine[70]
fizike interagas kun
medikamenta kategorio pri gravedo
Aŭstralia medikamenta prigraveda kategorio A
Usona medikamenta prigraveda kategorio B
LiverTox likelihood score
LiverTox toxicity likelihood category A[76]
varomarko
Erythrocin
subjekto havas rolon
gastrointestinal agent[79]
WHO Aware Classification
watch[83]
Komuneja kategorio
Erythromycin
Referenco
- ↑ 1,0 1,1 1,2 1,3 1,4 1,5 Global Substance Registration System, 17 nov. 2016, angla lingvo, erythromycin, 63937KV33D
- ↑ CAS Common Chemistry, 8 apr. 2021, ULGZDMOVFRHVEP-RWJQBGPGSA-N, https://commonchemistry.cas.org/detail?cas_rn=114-07-8
- ↑ 3,0 3,1 ChEMBL, 17 nov. 2016, angla lingvo, ERYTHROMYCIN, CHEMBL532
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17 nov. 2016, angla lingvo, 1456, erythromycin-A
- ↑ ECHA Substance Infocard database, 27 dec. 2018, 100.003.673, Erythromycin, CAS no.: 114-07-8
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4ZJQ, 4ZJQ
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 1YI2, 1YI2
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 3AOC, 3AOC
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 3J7Z, 3J7Z
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4M83, 4M83
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4V7X, 4V7X
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4V7U, 4V7U
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 3J5L, 3J5L
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 5JTE, 5JTE
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 2J0D, 2J0D
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 3FRQ, 3FRQ
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 5JU8, 5JU8
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4ZJL, 4ZJL
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4ZJO, 4ZJO
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 2IYF, 2IYF
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 4WFN, 4WFN
- ↑ Proteina Datenbazo, 19 okt. 2016, angla lingvo, 1JZY, 1JZY
- ↑ 23,0 23,1 UniChem
- ↑ 24,0 24,1 Cambridge Structural Database, 10 jan. 2023, InChIKey match
- ↑ 25,0 25,1 25,2 25,3 Kemiaj Entoj de Biologia Intereso, 19 okt. 2016, angla lingvo, erythromycin A, 42355
- ↑ 26,0 26,1 26,2 26,3 26,4 26,5 26,6 PubChem, 17 nov. 2016, angla lingvo, 12560, erythromycin
- ↑ 27,0 27,1 27,2 27,3 27,4 27,5 ULGZDMOVFRHVEP-RWJQBGPGSA-N, InChIKey
- ↑ Quora
- ↑ OpenAlex, 26 jan. 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
- ↑ 30,0 30,1 30,2 DrugBank, angla lingvo, 17 nov. 2015, 00199, Erythromycin
- ↑ KBpedia, 9 jul. 2020
- ↑ CAB Thesaurus, 6 apr. 2020
- ↑ ChEBI release 2020-09-01
- ↑ 34,0 34,1 inferred from InChIKey
- ↑ ChEBI release 2019-10-02
- ↑ Internacia Kemia Identigilo, InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
- ↑ GF WordNet
- ↑ ChemSpider, 17 nov. 2016, angla lingvo, 12041, (-)-Erythromycin
- ↑ Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard
- ↑ Freebase Data Dumps, 28 okt. 2013
- ↑ Great Norwegian Encyclopedia, 29 maj. 2020
- ↑ Hazardous Substances Data Bank, 10 maj. 2021, 28 okt. 2019, Erythromycin, 3074
- ↑ DrugBank, angla lingvo, 17 nov. 2015, Erythromycin, 00199
- ↑ inferred from InChI
- ↑ RxNorm, 750836, 14 feb. 2018
- ↑ RxNorm, 645943, 14 feb. 2018
- ↑ RxNorm, 202609, 14 feb. 2018
- ↑ RxNorm, 202614, 14 feb. 2018
- ↑ RxNorm, 203253, 14 feb. 2018
- ↑ RxNorm, 848114, 14 feb. 2018
- ↑ RxNorm, 798130, 14 feb. 2018
- ↑ RxNorm, 605264, 14 feb. 2018
- ↑ RxNorm, 216888, 14 feb. 2018
- ↑ RxNorm, 863600, 14 feb. 2018
- ↑ The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum
- ↑ Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain
- ↑ The Electrospray Ionization - Mass Spectra of Erythromycin A Obtained from a Marine Streptomyces sp. Mutant.
- ↑ Complete genome sequencing and antibiotics biosynthesis pathways analysis of Streptomyces lydicus 103.
- ↑ Genetic control of polyketide biosynthesis in the genus Streptomyces
- ↑ New antibiotics from genetically engineered actinomycetes. I. 2-Norerythromycins, isolation and structural determinations
- ↑ Isolation of erythromycin A N-oxide and pseudoerythromycin A hemiketal from fermentation broth of Saccharopolyspora erythraea by thin-layer and high-performance liquid chromatography
- ↑ Biosynthesis of erythromycin: origin of the methyl protons
- ↑ Macrolide biosynthesis. 6 Mechanism of polyketide chain elongation
- ↑ Metabolic Engineering Strategies Based on Secondary Messengers (p)ppGpp and C-di-GMP To Increase Erythromycin Yield in Saccharopolyspora erythraea
- ↑ 65,0 65,1 Erythromycin Biosynthesis: Kinetic Studies on a Fully Active Modular Polyketide Synthase Using Natural and Unnatural Substrates
- ↑ Characterization of a Cryptic NRPS Gene Cluster in Bacillus velezensis FZB42 Reveals a Discrete Oxidase Involved in Multithiazole Biosynthesis
- ↑ Enhancement of antibiotic activity against multidrug-resistant bacteria by the efflux pump inhibitor 3,4-dibromopyrrole-2,5-dione isolated from a Pseudoalteromonas sp.
- ↑ 68,00 68,01 68,02 68,03 68,04 68,05 68,06 68,07 68,08 68,09 68,10 N0000145975, 13 dec. 2016, NDF-RT, angla lingvo
- ↑ WikiSkripta
- ↑ 70,00 70,01 70,02 70,03 70,04 70,05 70,06 70,07 70,08 70,09 70,10 70,11 70,12 70,13 70,14 70,15 70,16 70,17 70,18 70,19 70,20 70,21 70,22 70,23 70,24 70,25 70,26 70,27 70,28 70,29 70,30 70,31 70,32 70,33 70,34 70,35 70,36 High-priority drug–drug interactions for use in electronic health records
- ↑ 71,00 71,01 71,02 71,03 71,04 71,05 71,06 71,07 71,08 71,09 71,10 71,11 71,12 71,13 71,14 71,15 71,16 71,17 71,18 71,19 71,20 71,21 71,22 71,23 71,24 71,25 71,26 71,27 71,28 71,29 71,30 71,31 71,32 71,33 71,34 71,35 71,36 71,37 71,38 71,39 71,40 71,41 71,42 71,43 71,44 71,45 71,46 71,47 71,48 71,49 71,50 71,51 71,52 71,53 71,54 71,55 71,56 71,57 71,58 71,59 71,60 71,61 71,62 71,63 71,64 71,65 71,66 71,67 71,68 71,69 71,70 71,71 71,72 71,73 71,74 71,75 A reference set of clinically relevant adverse drug-drug interactions, hipoteze
- ↑ 72,00 72,01 72,02 72,03 72,04 72,05 72,06 72,07 72,08 72,09 72,10 72,11 72,12 72,13 72,14 72,15 72,16 72,17 72,18 72,19 72,20 72,21 72,22 72,23 72,24 72,25 72,26 72,27 72,28 72,29 72,30 72,31 72,32 72,33 72,34 72,35 A reference set of clinically relevant adverse drug-drug interactions, probable
- ↑ 73,0 73,1 73,2 73,3 73,4 73,5 73,6 73,7 A reference set of clinically relevant adverse drug-drug interactions, established
- ↑ IUPHAR/BPS Guide to PHARMACOLOGY, 17 aŭg. 2016, 1456, angla lingvo
- ↑ The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors
- ↑ LiverTox, 8 apr. 2021, https://www.ncbi.nlm.nih.gov/books/n/livertox/Erythromycin, 10 aŭg. 2017
- ↑ BitterDB
- ↑ N0000145975, 5 mar. 2018, NDF-RT
- ↑ 79,0 79,1 79,2 Medical Subject Headings, 15 mar. 2018, D004917
- ↑ Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)
- ↑ Effects of low concentrations of erythromycin, penicillin, and virginiamycin on bacterial resistance development in vitro
- ↑ Genomic epidemiology of erythromycin-resistant Bordetella pertussis in China
- ↑ 2023 AWaRe classification